Learn all about Simparica for dogs cost, side effects, reviews and safety. Simparica (sarolaner) was just introduced in March 2016.
It is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Amblyomma Americanism (Lone Star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)]. Simparica begins to kill adult fleas within 3 hours and ticks within 8 hours of administration. Treatment with Simparica may begin at any time of the year and is safe to use year-round without interruption. Simparica is given monthly and requires a prescription from your veterinarian.
Simparica orally administered flea and tick treatment for dog is a monthly treatment that can be given with or without the food. One chewable tablet per month is enough to treat and protect your dog against flea infestation and to control the tick infestation. Simparica contains the active ingredient Sarolaner, which inhibits the function of the neurotransmitter gamma amino butyric acid (GABA) receptor and glutamate receptor, and works at the neuromuscular spot in insects. This results in uncontrolled neuromuscular activity leading to death in insects or acarines. It is easy and safe to administer, by directly giving it into the dog’s mouth or mixing it with food for rapidly killing the fleas and ticks.
The most frequently reported adverse reactions were vomiting and diarrhea. Simparica may cause abnormal neurologic signs such as tremors, decreased conscious proprioception (awareness of body position and movement), ataxia (loss of full control of bodily movements), decreased or absent menace blinking reflex or seizures.
Sarolaner was safe, achieved 100% reduction in the numbers of S. scabiei detected and resulted in marked improvement of the clinical signs of sarcoptic mange in dogs following two monthly oral administrations.
Simparica for Dogs
Simparica is a fast-acting oral flea and tick preventative that begins killing fleas and ticks within hours of administration and remains effective for one month to prevent re-infestations. Simparica (sarolaner) Chewables are safe, monthly flea and tick protection for dogs that start working fast and remain effective all month long. Simparica starts killing fleas within 3 hours and ticks within 8 hours, and it keeps going strong for 35 days without losing effectiveness at the end of the month.
Simparica is orally administered to dog that are 6 months of age or older and weighing more than 2.8lbs. Available in six different packs categorized as per the dog’s body weight, the chewable are suitable for all breeds and sizes of dogs. Simparica costs are according to weight and the pack size. The prices are listed below;
Simparica Chewables for Dogs 11.1-22 lbs (Brown)
3 Pack is of $34.13
6 Pack is of $58.93
Simparica Chewables for Dogs 2.8-5.5 lbs (Yellow)
3 Pack is of $31.14
6 Pack is of $52.34
Simparica Chewables for Dogs 5.6-11 lbs (Purple)
3 Pack is of $33.15
6 Pack is of $55.36
Simparica Chewables for Dogs 22.1-44 lbs (Blue)
3 Pack is of $36.13
6 Pack is of $60.38
Simparica Chewables for Dogs 44.1-88 lbs (Green)
3 Pack is of $38.07
6 Pack is of $62.36
Simparica Chewables for Dogs above 88 lbs (Red)
3 Pack is of $39.79
6 Pack is of $68.42
Simparica Side effects
Every drug has side effects. Simparica is for use only in dogs, 6 months of age and older. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and seizures. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. The most frequently reported adverse reactions were vomiting and diarrhea.
Simparica is effective against fleas and ticks, even on day. You can count on Simparica to do the following:
- Provide rapid relief for pets with existing flea infestations, even dogs with flea allergies
- Improve clinical signs of flea allergies in dogs by eliminating fleas
- Prevent and control home flea infestations, killing fleas before they can lay eggs
Some reviews are listed below;
- Quickly kill ticks, which may help reduce the risk of potentially life-threatening flea- and tick-borne diseases. One says, “It is a great product. I love how easy it is to give and that it covers my dog for fleas, ticks, mange and mites. My dog loved the tablet and thought she was getting a treat which is fantastic. This will be a regular purchase for our girl’’.
- One other review, “Usually I have to cover tablets with something tasty. Or crush them up and add them to his feed, but with the simparica chews it swallowed them straight away. I found them very effective, and the pooches had no nasty reactions to the chew which was a big sigh of relief’’.
Simparica efficacy and safety of a novel isoxazoline compound, sarolaner and spinosad as a positive control were evaluated for the treatment and control of natural flea infestations on dogs in two randomised, blinded, multi-centric clinical trials conducted in 11 veterinary clinics in northeastern and southeastern states of Australia. Sarolaner administered orally to provide a minimum dosage of 2.0 mg/kg (range 2–4 mg/kg) once monthly for three consecutive treatments was safe and effective in the treatment and prevention of natural infestations of fleas and resulted in a substantial improvement of clinical signs associated with FAD.